Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Chagas disease, leishmaniasis, and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually(1). The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp. and Trypanosoma brucei spp., respectively. These parasites...

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Publicat a:Nature
Autors principals: Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161665/
https://ncbi.nlm.nih.gov/pubmed/27501246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19339
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