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Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL)

Tetrahydrolipstatin (THL) is bactericidal but its precise target spectrum is poorly characterized. Here, we used a THL analog and activity-based protein profiling to identify target proteins after enrichment from whole cell lysates of Mycobacterium bovis Bacillus Calmette-Guérin cultured under repli...

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Détails bibliographiques
Auteurs principaux: Ravindran, Madhu Sudhan, Rao, Srinivasa P. S., Cheng, Xiamin, Shukla, Ankit, Cazenave-Gassiot, Amaury, Yao, Shao Q., Wenk, Markus R.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916645/
https://ncbi.nlm.nih.gov/pubmed/24345785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.029942
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