Genome-wide variant analysis of simplex autism families with an integrative clinical-bioinformatics pipeline

Por Jiménez-Barrón, Laura T., O'Rawe, Jason A., Wu, Yiyang, Yoon, Margaret, Fang, Han, Iossifov, Ivan, Lyon, Gholson J.
Publicado no Cold Spring Harb Mol Case Stud (2015)

BRCA2 is needed for both repair and cell cycle arrest in mammalian cells exposed to S23906, an anticancer monofunctional DNA binder

Por Rocca, Céline J, Soares, Daniele G, Bouzid, Hana, Henriques, João A P, Larsen, Annette K, Escargueil, Alexandre E
Publicado no Cell Cycle (2015)

EGFR signaling defines Mcl(-)1 survival dependency in neuroblastoma

Por Nalluri, Srilatha, Peirce, Susan K, Tanos, Rachel, Abdella, Haneen A, Karmali, Dipan, Hogarty, Michael D, Goldsmith, Kelly C
Publicado no Cancer Biol Ther (2015)

Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics

Por del Ama, Laura Fernandez, Jones, Mary, Walker, Paul, Chapman, Anna, Braun, Julia A., Mohr, Jasmine, Hurlstone, Adam F. L.
Publicado no Oncotarget (2016)

SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry

Por Bai, Ru, Zhang, Xing-Jie, Li, Yan-Li, Liu, Jing-Ping, Zhang, Hong-Bin, Xiao, Wei-Lie, Pu, Jian-Xin, Sun, Han-Dong, Zheng, Yong-Tang, Liu, Li-Xin
Publicado no BMC Microbiol (2015)

Multicomponent Synthesis of 3,6-Dihydro-2H-1,3-thiazine-2-thiones

Por Frans J. J. de Kanter, Eelco Ruijter, Romano V. A. Orru, Madeleine Helliwell, Elwin Janssen, Marten L. Ploeger, Art Kruithof
Publicado em 2012-02-01

Transcriptomic analysis of the response of Acropora millepora to hypo-osmotic stress provides insights into DMSP biosynthesis by corals

Por Aguilar, Catalina, Raina, Jean-Baptiste, Motti, Cherie A., Fôret, Sylvain, Hayward, David C., Lapeyre, Bruno, Bourne, David G., Miller, David J.
Publicado no BMC Genomics (2017)

Novel Benzoxazole Inhibitor of Dengue Virus Replication That Targets the NS3 Helicase

Por Byrd, Chelsea M., Grosenbach, Douglas W., Berhanu, Aklile, Dai, Dongcheng, Jones, Kevin F., Cardwell, Kara B., Schneider, Christine, Yang, Guang, Tyavanagimatt, Shanthakumar, Harver, Chris, Wineinger, Kristin A., Page, Jessica, Stavale, Eric, Stone, Melialani A., Fuller, Kathleen P., Lovejoy, Candace, Leeds, Janet M., Hruby, Dennis E., Jordan, Robert
Publicado em 2013

Identification of a small molecule inhibitor of importin beta mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries

Por Hintersteiner, Martin, Ambrus, Géza, Bednenko, Janna, Schmied, Mario, Knox, Andrew J.S., Gstach, Hubert, Seifert, Jan-Marcus, Singer, Eric L., Gerace, Larry, Auer, Manfred
Publicado em 2010

Development and Mining of a Volatile Organic Compound Database

Por Abdullah, Azian Azamimi, Altaf-Ul-Amin, Md., Ono, Naoaki, Sato, Tetsuo, Sugiura, Tadao, Morita, Aki Hirai, Katsuragi, Tetsuo, Muto, Ai, Nishioka, Takaaki, Kanaya, Shigehiko
Publicado no Biomed Res Int (2015)

Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number.

Por McAndrew, P E, Parsons, D W, Simard, L R, Rochette, C, Ray, P N, Mendell, J R, Prior, T W, Burghes, A H
Publicado em 1997

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

Por Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Publicado em 2010

Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa.

Por Winson, M K, Camara, M, Latifi, A, Foglino, M, Chhabra, S R, Daykin, M, Bally, M, Chapon, V, Salmond, G P, Bycroft, B W
Publicado em 1995

Quinolones Modulate Ghrelin Receptor Signaling: Potential for a Novel Small Molecule Scaffold in the Treatment of Cachexia

Por Cristina Torres-Fuentes, Elena Pastor-Cavada, Rafael Cano, Dalia Kandil, Rachel Shanahan, Rocio Juan, Hamdy Shaban, Gerard P. McGlacken, Harriët Schellekens
Publicado em 2018-05-01

Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor

Por Mitchell, Lorna H., Boriack-Sjodin, P. Ann, Smith, Sherri, Thomenius, Michael, Rioux, Nathalie, Munchhof, Michael, Mills, James E., Klaus, Christine, Totman, Jennifer, Riera, Thomas V., Raimondi, Alejandra, Jacques, Suzanne L., West, Kip, Foley, Megan, Waters, Nigel J., Kuntz, Kevin W., Wigle, Tim J., Scott, Margaret Porter, Copeland, Robert A., Smith, Jesse J., Chesworth, Richard
Publicado no ACS Med Chem Lett (2015)

Antiviral Compounds Discovered by Virtual Screening of Small–Molecule Libraries against Dengue Virus E Protein

Por Zhou, Zhigang, Khaliq, Mansoora, Suk, Jae-Eun, Patkar, Chinmay, Li, Long, Kuhn, Richard J., Post, Carol Beth
Publicado em 2008

Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs

Por Iwasa, T, Okamoto, I, Takezawa, K, Yamanaka, K, Nakahara, T, Kita, A, Koutoku, H, Sasamata, M, Hatashita, E, Yamada, Y, Kuwata, K, Fukuoka, M, Nakagawa, K
Publicado em 2010

Ascaroside Expression in Caenorhabditis elegans Is Strongly Dependent on Diet and Developmental Stage

Por Kaplan, Fatma, Srinivasan, Jagan, Mahanti, Parag, Ajredini, Ramadan, Durak, Omer, Nimalendran, Rathika, Sternberg, Paul W., Teal, Peter E. A., Schroeder, Frank C., Edison, Arthur S., Alborn, Hans T.
Publicado em 2011

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Por Hu, Zhi, Mao, Jian-Hua, Curtis, Christina, Huang, Ge, Gu, Shenda, Heiser, Laura, Lenburg, Marc E., Korkola, James E., Bayani, Nora, Samarajiwa, Shamith, Seoane, Jose A., A. Dane, Mark, Esch, Amanda, Feiler, Heidi S., Wang, Nicholas J., Hardwicke, Mary Ann, Laquerre, Sylvie, Jackson, Jeff, W. Wood, Kenneth, Weber, Barbara, Spellman, Paul T., Aparicio, Samuel, Wooster, Richard, Caldas, Carlos, Gray, Joe W.
Publicado no Breast Cancer Res (2016)

Large Contiguous Gene Deletions in Sjögren-Larsson Syndrome

Por Engelstad, Holly, Carney, Gael, S'Aulis, Dana, Rise, Janae, Sanger, Warren G., Rudd, M. Katharine, Richard, Gabriele, Carr, Christopher W., Abdul-Rahman, Omar A., Rizzo, William B.
Publicado em 2011