Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIα is regulated directly by protein phosphatase 2A

Por Escargueil, Alexandre E., Larsen, Annette K.
Publicado em 2007

The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane

Por Garrigues, Alexia, Escargueil, Alexandre E., Orlowski, Stéphane
Publicado em 2002

Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by ninteda...

Por Mésange, Paul, Poindessous, Virginie, Sabbah, Michèle, Escargueil, Alexandre E., de Gramont, Aimery, Larsen, Annette K.
Publicado em 2014

BRCA2 is needed for both repair and cell cycle arrest in mammalian cells exposed to S23906, an anticancer monofunctional DNA binder

Por Rocca, Céline J, Soares, Daniele G, Bouzid, Hana, Henriques, João A P, Larsen, Annette K, Escargueil, Alexandre E
Publicado no Cell Cycle (2015)

Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743

Por Soares, Daniele Grazziotin, Escargueil, Alexandre E., Poindessous, Virginie, Sarasin, Alain, de Gramont, Aimery, Bonatto, Diego, Henriques, João Antonio Pêgas, Larsen, Annette K.
Publicado em 2007

Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair

Por Lima, Michelle, Bouzid, Hana, Soares, Daniele G., Selle, Frédéric, Morel, Claire, Galmarini, Carlos M., Henriques, João A. P., Larsen, Annette K., Escargueil, Alexandre E.
Publicado no Oncotarget (2016)