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Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIα is regulated directly by protein phosphatase 2A

Recent results suggest a role for topoIIα (topoisomerase IIα) in the fine-tuning of mitotic entry. Mitotic entry is accompanied by the formation of specific phosphoepitopes such as MPM-2 (mitotic protein monoclonal 2) that are believed to control mitotic processes. Surprisingly, the MPM-2 kinase of...

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Detalhes bibliográficos
Main Authors: Escargueil, Alexandre E., Larsen, Annette K.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874246/
https://ncbi.nlm.nih.gov/pubmed/17212588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061460
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