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SUMO-2/3 regulates topoisomerase II in mitosis

We have analyzed the abundance of SUMO-conjugated species during the cell cycle in Xenopus egg extracts. The predominant SUMO conjugation products associated with mitotic chromosomes arose from SUMO conjugation of topoisomerase II. Topoisomerase II was modified exclusively by SUMO-2/3 during mitosis...

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Detalhes bibliográficos
Main Authors: Azuma, Yoshiaki, Arnaoutov, Alexei, Dasso, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173648/
https://ncbi.nlm.nih.gov/pubmed/14597774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304088
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