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The SUMO protease SENP6 is essential for inner kinetochore assembly
We have analyzed the mitotic function of SENP6, a small ubiquitin-like modifier (SUMO) protease that disassembles conjugated SUMO-2/3 chains. Cells lacking SENP6 showed defects in spindle assembly and metaphase chromosome congression. Analysis of kinetochore composition in these cells revealed that...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835930/ https://ncbi.nlm.nih.gov/pubmed/20212317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909008 |
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