Dynamics of human DNA topoisomerases IIα and IIβ in living cells

DNA topoisomerase (topo) II catalyses topological genomic changes essential for many DNA metabolic processes. It is also regarded as a structural component of the nuclear matrix in interphase and the mitotic chromosome scaffold. Mammals have two isoforms (α and β) with similar properties in vitro. H...

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Auteurs principaux: Christensen, Morten O., Larsen, Morten K., Barthelmes, Hans Ullrich, Hock, Robert, Andersen, Claus L., Kjeldsen, Eigil, Knudsen, Birgitta R., Westergaard, Ole, Boege, Fritz, Mielke, Christian
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2002
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173268/
https://ncbi.nlm.nih.gov/pubmed/11927602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112023
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