A carregar...
Residues 190–210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro
DNA-topoisomerase I (topo I) unwinds the DNA- double helix by cutting one strand and allowing rotation of the other. In vitro, this function does not require the N-terminal domain of the enzyme, which is believed to regulate cellular properties. To assess this role, we studied the cellular distribut...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14654701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg927 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|