Lanean...

Residues 190–210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro

DNA-topoisomerase I (topo I) unwinds the DNA- double helix by cutting one strand and allowing rotation of the other. In vitro, this function does not require the N-terminal domain of the enzyme, which is believed to regulate cellular properties. To assess this role, we studied the cellular distribut...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Christensen, Morten O., Barthelmes, Hans U., Boege, Fritz, Mielke, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC291868/
https://ncbi.nlm.nih.gov/pubmed/14654701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg927
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!