C-Terminal regions of topoisomerase IIα and IIβ determine isoform-specific functioning of the enzymes in vivo

Topoisomerase II removes supercoils and catenanes generated during DNA metabolic processes such as transcription and replication. Vertebrate cells express two genetically distinct isoforms (α and β) with similar structures and biochemical activities but different biological roles. Topoisomerase IIα...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Linka, René M., Porter, Andrew C.G., Volkov, Arsen, Mielke, Christian, Boege, Fritz, Christensen, Morten O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2007
Ämnen:
Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920234/
https://ncbi.nlm.nih.gov/pubmed/17526531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm102
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk