C-Terminal regions of topoisomerase IIα and IIβ determine isoform-specific functioning of the enzymes in vivo

Topoisomerase II removes supercoils and catenanes generated during DNA metabolic processes such as transcription and replication. Vertebrate cells express two genetically distinct isoforms (α and β) with similar structures and biochemical activities but different biological roles. Topoisomerase IIα...

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Detaylı Bibliyografya
Asıl Yazarlar: Linka, René M., Porter, Andrew C.G., Volkov, Arsen, Mielke, Christian, Boege, Fritz, Christensen, Morten O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2007
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920234/
https://ncbi.nlm.nih.gov/pubmed/17526531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm102
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