Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint

Topoisomerase (topo) IIα and IIβ maintain genome stability and are targets for anti-tumor drugs. In this study, we demonstrate that the decatenation checkpoint is regulated, not only by topo IIα, as previously reported, but also by topo IIβ. The decatenation checkpoint is most efficient when both is...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Kozuki, Toshiyuki, Chikamori, Kenichi, Surleac, Marius D., Micluta, Marius A., Petrescu, Andrei J., Norris, Eric J., Elson, Paul, Hoeltge, Gerald A., Grabowski, Dale R., Porter, Andrew C.G., Ganapathi, Ram N., Ganapathi, Mahrukh K.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Nucleic Acid Enzymes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449615/
https://ncbi.nlm.nih.gov/pubmed/28472494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx325
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires