Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint

Topoisomerase (topo) IIα and IIβ maintain genome stability and are targets for anti-tumor drugs. In this study, we demonstrate that the decatenation checkpoint is regulated, not only by topo IIα, as previously reported, but also by topo IIβ. The decatenation checkpoint is most efficient when both is...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Kozuki, Toshiyuki, Chikamori, Kenichi, Surleac, Marius D., Micluta, Marius A., Petrescu, Andrei J., Norris, Eric J., Elson, Paul, Hoeltge, Gerald A., Grabowski, Dale R., Porter, Andrew C.G., Ganapathi, Ram N., Ganapathi, Mahrukh K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Nucleic Acid Enzymes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449615/
https://ncbi.nlm.nih.gov/pubmed/28472494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx325
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