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Topoisomerase IIα controls the decatenation checkpoint

Topoisomerase II (Topo II) is required to separate intertwined sister chromatids before chromosome segregation can occur in mitosis1. However, it remains to be resolved whether Topo II has any role in checkpoint control. Here we report that when phosphorylated, Ser 1524 of Topo IIα acts as a binding...

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Detaylı Bibliyografya
Asıl Yazarlar: Luo, Kuntian, Yuan, Jian, Chen, Junjie, Lou, Zhenkun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712943/
https://ncbi.nlm.nih.gov/pubmed/19098900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1828
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