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MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks
The product of the Nijmegen breakage syndrome gene (NBS1) plays crucial roles in DNA damage response through its association with many proteins, including MRE11 and RAD50. However, it remains to be determined exactly how NBS1 accumulates at or near DNA double-strand breaks. Here we report that MDC1...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516250/ https://ncbi.nlm.nih.gov/pubmed/18678890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802885105 |
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