Oligomerization of MDC1 Protein Is Important for Proper DNA Damage Response

von Luo, Kuntian, Yuan, Jian, Lou, Zhenkun
Veröffentlicht 2011

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

von Wu, Liming, Luo, Kuntian, Lou, Zhenkun, Chen, Junjie
Veröffentlicht 2008

Topoisomerase IIα controls the decatenation checkpoint

von Luo, Kuntian, Yuan, Jian, Chen, Junjie, Lou, Zhenkun
Veröffentlicht 2008

Regulation of SIRT1 activity by genotoxic stress

von Yuan, Jian, Luo, Kuntian, Liu, Tongzheng, Lou, Zhenkun
Veröffentlicht 2012

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

von Yuan, Jian, Luo, Kuntian, Zhang, Lizhi, Cheville, John, Lou, Zhenkun
Veröffentlicht 2010

Sumoylation of MDC1 is important for proper DNA damage response

von Luo, Kuntian, Zhang, Haoxing, Wang, Liewei, Yuan, Jian, Lou, Zhenkun
Veröffentlicht 2012

CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase

von Luo, Kuntian, Deng, Min, Li, Yunhui, Wu, Chenming, Xu, Ziwen, Yuan, Jian, Lou, Zhenkun
Veröffentlicht in Nucleic Acids Res (2015)

A novel topoisomerase I inhibitor DIA-001 induces DNA damage mediated cell cycle arrest and apoptosis in cancer cell

von Liu, Jiaqi, Geng, Guohe, Liang, Guang, Wang, Ling, Luo, Kuntian, Yuan, Jian, Zhao, Shiguang
Veröffentlicht in Ann Transl Med (2020)

HERC2-USP20 axis regulates DNA damage checkpoint through Claspin

von Yuan, Jian, Luo, Kuntian, Deng, Min, Li, Yunhui, Yin, Ping, Gao, Bowen, Fang, Yuan, Wu, Puqiang, Liu, Tongzheng, Lou, Zhenkun
Veröffentlicht in Nucleic Acids Res (2014)

A phosphorylation–deubiquitination cascade regulates the BRCA2–RAD51 axis in homologous recombination

von Luo, Kuntian, Li, Lei, Li, Yunhui, Wu, Chenming, Yin, Yujiao, Chen, Yuping, Deng, Min, Nowsheen, Somaira, Yuan, Jian, Lou, Zhenkun
Veröffentlicht in Genes Dev (2016)

USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response

von Li, Yunhui, Luo, Kuntian, Yin, Yujiao, Wu, Chenming, Deng, Min, Li, Lei, Chen, Yuping, Nowsheen, Somaira, Lou, Zhenkun, Yuan, Jian
Veröffentlicht in Nat Commun (2017)

SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response

von Guo, Guijie, Gao, Ming, Gao, Xiaochen, Zhu, Bibo, Huang, Jinzhou, Luo, Kuntian, Zhang, Yong, Sun, Jie, Deng, Min, Lou, Zhenkun
Veröffentlicht in Signal Transduct Target Ther (2021)

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

von Pei, Huadong, Zhang, Lindsey, Luo, Kuntian, Qin, Yuxin, Chesi, Marta, Fei, Frances, Bergsagel, P. Leif, Wang, Liewei, You, Zhongsheng, Lou, Zhenkun
Veröffentlicht 2011

USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51‐AKT signaling

von Luo, Kuntian, Li, Yunhui, Yin, Yujiao, Li, Lei, Wu, Chenming, Chen, Yuping, Nowsheen, Somaira, Hu, Qi, Zhang, Lizhi, Lou, Zhenkun, Yuan, Jian
Veröffentlicht in EMBO J (2017)

The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization

von Li, Lei, Liu, Tongzheng, Li, Yunhui, Wu, Chenming, Luo, Kuntian, Yin, Yujiao, Chen, Yuping, Nowsheen, Somaira, Wu, Jinhuan, Lou, Zhenkun, Yuan, Jian
Veröffentlicht in Oncogene (2018)

Resveratrol induces apoptosis by directly targeting Ras-GTPase activating protein SH3 domain binding protein 1 (G3BP1)

von Oi, Naomi, Yuan, Jian, Malakhova, Margarita, Luo, Kuntian, Li, Yunhui, Ryu, Joohyun, Zhang, Lei, Bode, Ann M., Xu, Zengguang, Li, Yan, Lou, Zhenkun, Dong, Zigang
Veröffentlicht in Oncogene (2014)

Chk1 inhibitor SCH 900776 enhances the antitumor activity of MLN4924 on pancreatic cancer

von Li, Jian-ang, Song, Chao, Rong, Yefei, Kuang, Tiantao, Wang, Dansong, Xu, Xuefeng, Yuan, Jian, Luo, Kuntian, Qin, Bo, Nowsheen, Somaira, Lou, Zhenkun, Lou, Wenhui
Veröffentlicht in Cell Cycle (2018)

A novel UCHL(3) inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair

von Song, Zhiwang, Tu, Xinyi, Zhou, Qin, Huang, Jinzhou, Chen, Yuping, Liu, Jiaqi, Lee, SeungBaek, Kim, Wootae, Nowsheen, Somaira, Luo, Kuntian, Yuan, Jian, Lou, Zhenkun
Veröffentlicht in Cell Death Dis (2019)

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization

von Yan, Yuanliang, Xu, Zhijie, Huang, Jinzhou, Guo, Guijie, Gao, Ming, Kim, Wootae, Zeng, Xiangyu, Kloeber, Jake A, Zhu, Qian, Zhao, Fei, Luo, Kuntian, Lou, Zhenkun
Veröffentlicht in Nucleic Acids Res (2020)

ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex

von Kim, Wootae, Zhao, Fei, Wu, Rentian, Qin, Sisi, Nowsheen, Somaira, Huang, Jinzhou, Zhou, Qin, Chen, Yuping, Deng, Min, Guo, Guijie, Luo, Kuntian, Lou, Zhenkun, Yuan, Jian
Veröffentlicht in Nat Commun (2019)