USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51‐AKT signaling

The AKT pathway is a fundamental signaling pathway that mediates multiple cellular processes, such as cell proliferation and survival, angiogenesis, and glucose metabolism. We recently reported that the immunophilin FKBP51 is a scaffolding protein that can enhance PHLPP‐AKT interaction and facilitat...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Luo, Kuntian, Li, Yunhui, Yin, Yujiao, Li, Lei, Wu, Chenming, Chen, Yuping, Nowsheen, Somaira, Hu, Qi, Zhang, Lizhi, Lou, Zhenkun, Yuan, Jian
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430216/
https://ncbi.nlm.nih.gov/pubmed/28363942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695669
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