The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization

The Yes-associated protein 1 (YAP1), a major downstream effector of the Hippo pathway, functions as a transcriptional regulator and plays an important role in cellular control of organ size and tumor growth. Elevated oncogenic activity of YAP1 has been clarified in different types of human cancers,...

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Vydáno v:Oncogene
Hlavní autoři: Li, Lei, Liu, Tongzheng, Li, Yunhui, Wu, Chenming, Luo, Kuntian, Yin, Yujiao, Chen, Yuping, Nowsheen, Somaira, Wu, Jinhuan, Lou, Zhenkun, Yuan, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940338/
https://ncbi.nlm.nih.gov/pubmed/29449692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0134-2
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