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The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization
The Yes-associated protein 1 (YAP1), a major downstream effector of the Hippo pathway, functions as a transcriptional regulator and plays an important role in cellular control of organ size and tumor growth. Elevated oncogenic activity of YAP1 has been clarified in different types of human cancers,...
Tallennettuna:
| Julkaisussa: | Oncogene |
|---|---|
| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5940338/ https://ncbi.nlm.nih.gov/pubmed/29449692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0134-2 |
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