USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response

BRCA1 regulates multiple cellular pathways that maintain genomic stability including cell cycle checkpoints, DNA repair, protein ubiquitination, chromatin remodelling, transcriptional regulation and apoptosis. Receptor-associated protein 80 (RAP80) helps recruit BRCA1 to double-strand breaks (DSBs)...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Li, Yunhui, Luo, Kuntian, Yin, Yujiao, Wu, Chenming, Deng, Min, Li, Lei, Chen, Yuping, Nowsheen, Somaira, Lou, Zhenkun, Yuan, Jian
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461494/
https://ncbi.nlm.nih.gov/pubmed/28569838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15752
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