HERC2-USP20 axis regulates DNA damage checkpoint through Claspin

The DNA damage response triggers cell-cycle checkpoints, DNA repair and apoptosis using multiple post-translational modifications as molecular switches. However, how ubiquitination regulates ATR signaling in response to replication stress and single-strand break is still unclear. Here, we identified...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Yuan, Jian, Luo, Kuntian, Deng, Min, Li, Yunhui, Yin, Ping, Gao, Bowen, Fang, Yuan, Wu, Puqiang, Liu, Tongzheng, Lou, Zhenkun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Genome Integrity, Repair and Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245938/
https://ncbi.nlm.nih.gov/pubmed/25355518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1034
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