CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase

There are the two major pathways responsible for the repair of DNA double-strand breaks (DSBs): non-homologous end-joining (NHEJ) and homologous recombination (HR). NHEJ operates throughout the cell-cycle, while HR is primarily active in the S/G2 phases suggesting that there are cell cycle-specific...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Luo, Kuntian, Deng, Min, Li, Yunhui, Wu, Chenming, Xu, Ziwen, Yuan, Jian, Lou, Zhenkun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477664/
https://ncbi.nlm.nih.gov/pubmed/25948581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv434
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