Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

DNA double-strand break (DSB) repair via the homologous recombination pathway is a multi-stage process, which results in repair of the DSB without loss of genetic information or fidelity. One essential step in this process is the generation of extended single-stranded DNA (ssDNA) regions at the brea...

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Autores principales: Bolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J., Boucher, Didier, Kumar, Rakesh, Pandita, Tej K., Burma, Sandeep, Khanna, Kum Kum
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847229/
https://ncbi.nlm.nih.gov/pubmed/20019063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1164
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