Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks

Aberrant DNA replication is a primary cause of mutations that are associated with pathological disorders including cancer. During DNA metabolism, the primary causes of replication fork stalling include secondary DNA structures, highly transcribed regions and damaged DNA. The restart of stalled repli...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bolderson, Emma, Petermann, Eva, Croft, Laura, Suraweera, Amila, Pandita, Raj K., Pandita, Tej K., Helleday, Thomas, Khanna, Kum Kum, Richard, Derek J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Genome Integrity, Repair and Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041449/
https://ncbi.nlm.nih.gov/pubmed/24753408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku276
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires