Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks

Aberrant DNA replication is a primary cause of mutations that are associated with pathological disorders including cancer. During DNA metabolism, the primary causes of replication fork stalling include secondary DNA structures, highly transcribed regions and damaged DNA. The restart of stalled repli...

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Bibliografiske detaljer
Main Authors: Bolderson, Emma, Petermann, Eva, Croft, Laura, Suraweera, Amila, Pandita, Raj K., Pandita, Tej K., Helleday, Thomas, Khanna, Kum Kum, Richard, Derek J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041449/
https://ncbi.nlm.nih.gov/pubmed/24753408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku276
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