hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response

hSSB1 (human single strand DNA-binding protein 1) has been shown to participate in homologous recombination (HR)-dependent repair of DNA double strand breaks (DSBs) and ataxia telangiectasia-mutated (ATM)-mediated checkpoint pathways. Here we present evidence that hSSB2, a homolog of hSSB1, plays a...

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Main Authors: Li, Yongjiang, Bolderson, Emma, Kumar, Rakesh, Muniandy, Parameswary A., Xue, Yutong, Richard, Derek J., Seidman, Michael, Pandita, Tej K., Khanna, Kum Kum, Wang, Weidong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749126/
https://ncbi.nlm.nih.gov/pubmed/19605351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.039586
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