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hSSB1 associates with and promotes stability of the BLM helicase

BACKGROUND: Maintenance of genome stability is critical in human cells. Mutations in or loss of genome stability pathways can lead to a number of pathologies including cancer. hSSB1 is a critical DNA repair protein functioning in the repair and signalling of stalled DNA replication forks, double str...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Croft, Laura V., Ashton, Nicholas W., Paquet, Nicolas, Bolderson, Emma, O’Byrne, Kenneth J., Richard, Derek J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433028/
https://ncbi.nlm.nih.gov/pubmed/28506294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-017-0090-3
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