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CHECKPOINT RESPONSES TO DNA DOUBLE-STRAND BREAKS
Cells confront DNA damage in every cell cycle. Among the most deleterious types of DNA damage are DNA double-strand breaks, which can cause cell lethality if unrepaired or cancers if improperly repaired. In response to DNA double-strand breaks, cells activate a complex DNA damage checkpoint (DDC) re...
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| Publicado no: | Annu Rev Biochem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7311309/ https://ncbi.nlm.nih.gov/pubmed/32176524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-011520-104722 |
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