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Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

DNA is subject to many endogenous and exogenous insults that impair DNA replication and proper chromosome segregation. DNA double-strand breaks (DSBs) are one of the most toxic of these lesions and must be repaired to preserve chromosomal integrity. Eukaryotes are equipped with several different, bu...

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Hlavní autoři: Mehta, Anuja, Haber, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142968/
https://ncbi.nlm.nih.gov/pubmed/25104768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016428
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