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Homologous recombination and the repair of DNA double-strand breaks

Homologous recombination enables the cell to access and copy intact DNA sequence information in trans, particularly to repair DNA damage affecting both strands of the double helix. Here, we discuss the DNA transactions and enzymatic activities required for this elegantly orchestrated process in the...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Wright, William Douglass, Shah, Shanaya Shital, Heyer, Wolf-Dietrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036207/
https://ncbi.nlm.nih.gov/pubmed/29599286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.000372
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