Homologous recombination and the repair of DNA double-strand breaks

Homologous recombination enables the cell to access and copy intact DNA sequence information in trans, particularly to repair DNA damage affecting both strands of the double helix. Here, we discuss the DNA transactions and enzymatic activities required for this elegantly orchestrated process in the...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Wright, William Douglass, Shah, Shanaya Shital, Heyer, Wolf-Dietrich
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Thematic Minireviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036207/
https://ncbi.nlm.nih.gov/pubmed/29599286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.000372
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