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Nonhomologous DNA end-joining for repair of DNA double-strand breaks

Nonhomologous DNA end-joining (NHEJ) is the predominant double-strand break (DSB) repair pathway throughout the cell cycle and accounts for nearly all DSB repair outside of the S and G(2) phases. NHEJ relies on Ku to thread onto DNA termini and thereby improve the affinity of the NHEJ enzymatic comp...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Pannunzio, Nicholas R., Watanabe, Go, Lieber, Michael R.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036208/
https://ncbi.nlm.nih.gov/pubmed/29247009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM117.000374
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