CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair

The repair of DNA double-strand breaks (DSBs) is mediated via two major pathways, nonhomologous end joining (NHEJ) and homologous recombination (HR) repair. DSB repair is vital for cell survival, genome stability, and tumor suppression. In contrast to NHEJ, HR relies on extensive homology and templa...

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Bibliografiska uppgifter
I publikationen:Sci Adv
Huvudupphovsmän: Hilmi, Khalid, Jangal, Maïka, Marques, Maud, Zhao, Tiejun, Saad, Amine, Zhang, Chenxi, Luo, Vincent M., Syme, Alasdair, Rejon, Carlis, Yu, Zhenbao, Krum, Asiev, Fabian, Marc R., Richard, Stéphane, Alaoui-Jamali, Moulay, Orthwein, Alexander, McCaffrey, Luke, Witcher, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Association for the Advancement of Science 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443639/
https://ncbi.nlm.nih.gov/pubmed/28560323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601898
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