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Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair
DNA is subject to many endogenous and exogenous insults that impair DNA replication and proper chromosome segregation. DNA double-strand breaks (DSBs) are one of the most toxic of these lesions and must be repaired to preserve chromosomal integrity. Eukaryotes are equipped with several different, bu...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142968/ https://ncbi.nlm.nih.gov/pubmed/25104768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016428 |
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