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Asf1 facilitates dephosphorylation of Rad53 after DNA double-strand break repair

To allow for sufficient time to repair DNA double-stranded breaks (DSBs), eukaryotic cells activate the DNA damage checkpoint. In budding yeast, Rad53 (mammalian Chk2) phosphorylation parallels the persistence of the unrepaired DSB and is extinguished when repair is complete in a process termed reco...

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Publicat a:Genes Dev
Autors principals: Tsabar, Michael, Waterman, David P., Aguilar, Fiona, Katsnelson, Lizabeth, Eapen, Vinay V., Memisoglu, Gonen, Haber, James E.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888841/
https://ncbi.nlm.nih.gov/pubmed/27222517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.280685.116
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