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Topoisomerase IIα controls the decatenation checkpoint

Topoisomerase II (Topo II) is required to separate intertwined sister chromatids before chromosome segregation can occur in mitosis1. However, it remains to be resolved whether Topo II has any role in checkpoint control. Here we report that when phosphorylated, Ser 1524 of Topo IIα acts as a binding...

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Bibliographic Details
Main Authors: Luo, Kuntian, Yuan, Jian, Chen, Junjie, Lou, Zhenkun
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712943/
https://ncbi.nlm.nih.gov/pubmed/19098900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1828
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