Topoisomerase IIα maintains genomic stability through decatenation G(2) checkpoint signaling

Topoisomerase IIα (topoIIα) is an essential mammalian enzyme that topologically modifies DNA and is required for chromosome segregation during mitosis. Previous research suggests that inhibition of topoII decatenatory activity triggers a G(2) checkpoint response, which delays mitotic entry due to in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bower, Jacquelyn J., Karaca, Gamze F., Zhou, Yingchun, Simpson, Dennis A., Cordeiro-Stone, Marila, Kaufmann, William K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928865/
https://ncbi.nlm.nih.gov/pubmed/20562910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.232
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak