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The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane
P-glycoprotein (P-gp) is a plasma membrane ATP-binding cassette transporter, responsible for multidrug resistance in tumor cells. P-gp catalyzes the ATP hydrolysis-dependent efflux of numerous amphiphilic compounds of unrelated chemical structures. In the absence of any identified substrate, P-gp ex...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124917/ https://ncbi.nlm.nih.gov/pubmed/12145328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162366399 |
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