Novel Benzoxazole Inhibitor of Dengue Virus Replication That Targets the NS3 Helicase

Dengue virus (DENV) is the predominant mosquito-borne viral pathogen that infects humans with an estimated 50 to 100 million infections per year worldwide. Over the past 50 years, the incidence of dengue disease has increased dramatically and the virus is now endemic in more than 100 countries. More...

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Autori principali: Byrd, Chelsea M., Grosenbach, Douglas W., Berhanu, Aklile, Dai, Dongcheng, Jones, Kevin F., Cardwell, Kara B., Schneider, Christine, Yang, Guang, Tyavanagimatt, Shanthakumar, Harver, Chris, Wineinger, Kristin A., Page, Jessica, Stavale, Eric, Stone, Melialani A., Fuller, Kathleen P., Lovejoy, Candace, Leeds, Janet M., Hruby, Dennis E., Jordan, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623359/
https://ncbi.nlm.nih.gov/pubmed/23403421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02251-12
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