Development of ST-246® for Treatment of Poxvirus Infections

Por Jordan, Robert, Leeds, Janet M., Tyavanagimatt, Shanthakumar, Hruby, Dennis E.
Publicado em 2010

Pharmacokinetics and Interspecies Allometric Scaling of ST-246, an Oral Antiviral Therapeutic for Treatment of Orthopoxvirus Infection

Por Amantana, Adams, Chen, Yali, Tyavanagimatt, Shanthakumar R., Jones, Kevin F., Jordan, Robert, Chinsangaram, Jarasvech, Bolken, Tove′ C., Leeds, Janet M., Hruby, Dennis E.
Publicado em 2013

Inhibition of Human Immunodeficiency Virus Type 1 Infection in SCID-hu Thy/Liv Mice by the G-Quartet-Forming Oligonucleotide, ISIS 5320

Por Stoddart, Cheryl A., Rabin, Linda, Hincenbergs, Mara, Moreno, Mary e., Linquist-Stepps, Valerie, Leeds, Janet M., Truong, Lo Anne, Wyatt, J. R., Ecker, David J., McCune, Joseph M.
Publicado em 1998

Pharmacokinetic and Pharmacodynamic Modeling To Determine the Dose of ST-246 To Protect against Smallpox in Humans

Por Leeds, Janet M., Fenneteau, Frederique, Gosselin, Nathalie H., Mouksassi, Mohamad-Samer, Kassir, Nastya, Marier, J. F., Chen, Yali, Grosenbach, Doug, Frimm, Annie E., Honeychurch, Kady M., Chinsangaram, Jarasvech, Tyavanagimatt, Shanthakumar R., Hruby, Dennis E., Jordan, Robert
Publicado em 2013

Safety and Pharmacokinetics of the Anti-Orthopoxvirus Compound ST-246 following a Single Daily Oral Dose for 14 Days in Human Volunteers

Por Chinsangaram, Jarasvech, Honeychurch, Kady M., Tyavanagimatt, Shanthakumar R., Leeds, Janet M., Bolken, Tove' C., Jones, Kevin F., Jordan, Robert, Marbury, Thomas, Ruckle, Jon, Mee-Lee, Denis, Ross, Eric, Lichtenstein, Israel, Pickens, Margaret, Corrado, Michael, Clarke, Jean M., Frimm, Annie M., Hruby, Dennis E.
Publicado em 2012

Novel Benzoxazole Inhibitor of Dengue Virus Replication That Targets the NS3 Helicase

Por Byrd, Chelsea M., Grosenbach, Douglas W., Berhanu, Aklile, Dai, Dongcheng, Jones, Kevin F., Cardwell, Kara B., Schneider, Christine, Yang, Guang, Tyavanagimatt, Shanthakumar, Harver, Chris, Wineinger, Kristin A., Page, Jessica, Stavale, Eric, Stone, Melialani A., Fuller, Kathleen P., Lovejoy, Candace, Leeds, Janet M., Hruby, Dennis E., Jordan, Robert
Publicado em 2013

Comparison of the Safety and Pharmacokinetics of ST-246® after IV Infusion or Oral Administration in Mice, Rabbits and Monkeys

Por Chen, Yali, Amantana, Adams, Tyavanagimatt, Shanthakumar R., Zima, Daniela, Yan, X. Steven, Kasi, Gopi, Weeks, Morgan, Stone, Melialani A., Weimers, William C., Samuel, Peter, Tan, Ying, Jones, Kevin F., Lee, Daniel R., Kickner, Shirley S., Saville, Bradley M., Lauzon, Martin, McIntyre, Alan, Honeychurch, Kady M., Jordan, Robert, Hruby, Dennis E., Leeds, Janet M.
Publicado em 2011