Pharmacokinetics and Interspecies Allometric Scaling of ST-246, an Oral Antiviral Therapeutic for Treatment of Orthopoxvirus Infection

Por Amantana, Adams, Chen, Yali, Tyavanagimatt, Shanthakumar R., Jones, Kevin F., Jordan, Robert, Chinsangaram, Jarasvech, Bolken, Tove′ C., Leeds, Janet M., Hruby, Dennis E.
Publicado em 2013

ST-246 Antiviral Efficacy in a Nonhuman Primate Monkeypox Model: Determination of the Minimal Effective Dose and Human Dose Justification

Por Jordan, Robert, Goff, Arthur, Frimm, Annie, Corrado, Michael L., Hensley, Lisa E., Byrd, Chelsea M., Mucker, Eric, Shamblin, Josh, Bolken, Tove' C., Wlazlowski, Carly, Johnson, Wendy, Chapman, Jennifer, Twenhafel, Nancy, Tyavanagimatt, Shanthakumar, Amantana, Adams, Chinsangaram, Jarasvech, Hruby, Dennis E., Huggins, John
Publicado em 2009

Comparison of the Safety and Pharmacokinetics of ST-246® after IV Infusion or Oral Administration in Mice, Rabbits and Monkeys

Por Chen, Yali, Amantana, Adams, Tyavanagimatt, Shanthakumar R., Zima, Daniela, Yan, X. Steven, Kasi, Gopi, Weeks, Morgan, Stone, Melialani A., Weimers, William C., Samuel, Peter, Tan, Ying, Jones, Kevin F., Lee, Daniel R., Kickner, Shirley S., Saville, Bradley M., Lauzon, Martin, McIntyre, Alan, Honeychurch, Kady M., Jordan, Robert, Hruby, Dennis E., Leeds, Janet M.
Publicado em 2011