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Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs
BACKGROUND: Survivin, a member of the inhibitor of apoptosis protein family, is an attractive target for cancer therapy. We have now investigated the effects of the combination of YM155, a novel small-molecule inhibitor of survivin expression, and platinum compounds (cisplatin and carboplatin) on hu...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905296/ https://ncbi.nlm.nih.gov/pubmed/20517311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605713 |
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