Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin

Survivin is responsible for cancer progression and drug resistance in many types of cancer. YM155 selectively suppresses the expression of survivin and induces apoptosis in cancer cells in vitro and in vivo. However, the mechanism underlying these effects of YM155 is unknown. Here, we show that a tr...

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Hauptverfasser: Nakamura, Naoto, Yamauchi, Tomohiro, Hiramoto, Masashi, Yuri, Masatoshi, Naito, Masanori, Takeuchi, Masahiro, Yamanaka, Kentaro, Kita, Aya, Nakahara, Takahito, Kinoyama, Isao, Matsuhisa, Akira, Kaneko, Naoki, Koutoku, Hiroshi, Sasamata, Masao, Yokota, Hiroyuki, Kawabata, Shigeki, Furuichi, Kiyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394938/
https://ncbi.nlm.nih.gov/pubmed/22442257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.013243
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