The over-expression of survivin enhances the chemotherapeutic efficacy of YM155 in human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. The inability of chemotherapeutic drugs to selectively target HCC tumor cells because of their predominant resistant phenotype to most conventional anticancer agents bestows a major obstacle for the clinic...

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Pubblicato in:Oncotarget
Autori principali: Xia, Hongping, Chen, Jianxiang, Shi, Ming, Deivasigamani, Amudha, P.J. Ooi, London Lucien, Hui, Kam M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467416/
https://ncbi.nlm.nih.gov/pubmed/25714025
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