Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

BACKGROUND: Pim family kinases are small constitutively active serine/threonine-specific kinases, elevated levels of which have been detected in human hematopoietic malignancies as well as in solid tumours. While we and others have previously shown that the oncogenic Pim kinases stimulate survival o...

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Bibliografiske detaljer
Main Authors:	Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2010
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2978147/ https://ncbi.nlm.nih.gov/pubmed/20958956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-279
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Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

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