Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

BACKGROUND: Pim family kinases are small constitutively active serine/threonine-specific kinases, elevated levels of which have been detected in human hematopoietic malignancies as well as in solid tumours. While we and others have previously shown that the oncogenic Pim kinases stimulate survival o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978147/
https://ncbi.nlm.nih.gov/pubmed/20958956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-279
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