Tricyclic Benzo[cd]azulenes Selectively Inhibit Activities of Pim Kinases and Restrict Growth of Epstein-Barr Virus-Transformed Cells

Oncogenic Pim family kinases are often overexpressed in human hematopoietic malignancies as well as in solid tumours. These kinases contribute to tumorigenesis by promoting cell survival and by enhancing resistance against chemotherapy and radiation therapy. Furthermore, we have recently shown that...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kiriazis, Alexandros, Vahakoski, Riitta L., Santio, Niina M., Arnaudova, Ralica, Eerola, Sini K., Rainio, Eeva-Marja, Aumüller, Ingo B., Yli-Kauhaluoma, Jari, Koskinen, Päivi J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566155/
https://ncbi.nlm.nih.gov/pubmed/23405147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055409
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