Tricyclic Benzo[cd]azulenes Selectively Inhibit Activities of Pim Kinases and Restrict Growth of Epstein-Barr Virus-Transformed Cells

Oncogenic Pim family kinases are often overexpressed in human hematopoietic malignancies as well as in solid tumours. These kinases contribute to tumorigenesis by promoting cell survival and by enhancing resistance against chemotherapy and radiation therapy. Furthermore, we have recently shown that...

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Detaylı Bibliyografya
Asıl Yazarlar: Kiriazis, Alexandros, Vahakoski, Riitta L., Santio, Niina M., Arnaudova, Ralica, Eerola, Sini K., Rainio, Eeva-Marja, Aumüller, Ingo B., Yli-Kauhaluoma, Jari, Koskinen, Päivi J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566155/
https://ncbi.nlm.nih.gov/pubmed/23405147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055409
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