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Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

BACKGROUND AND METHODS: Pim family proteins are oncogenic kinases implicated in several types of cancer and involved in regulation of cell proliferation, survival as well as motility. Here we have investigated the ability of Pim kinases to promote metastatic growth of prostate cancer cells in two xe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Santio, Niina M., Eerola, Sini K., Paatero, Ilkka, Yli-Kauhaluoma, Jari, Anizon, Fabrice, Moreau, Pascale, Tuomela, Johanna, Härkönen, Pirkko, Koskinen, Päivi J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467846/
https://ncbi.nlm.nih.gov/pubmed/26075720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130340
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