Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

BACKGROUND: Pim family kinases are small constitutively active serine/threonine-specific kinases, elevated levels of which have been detected in human hematopoietic malignancies as well as in solid tumours. While we and others have previously shown that the oncogenic Pim kinases stimulate survival o...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978147/
https://ncbi.nlm.nih.gov/pubmed/20958956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-279
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky