Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

BACKGROUND: Pim family kinases are small constitutively active serine/threonine-specific kinases, elevated levels of which have been detected in human hematopoietic malignancies as well as in solid tumours. While we and others have previously shown that the oncogenic Pim kinases stimulate survival o...

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Detalhes bibliográficos
Main Authors: Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978147/
https://ncbi.nlm.nih.gov/pubmed/20958956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-279
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