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Nuclear β-Catenin Is Increased in Systemic Sclerosis Pulmonary Fibrosis and Promotes Lung Fibroblast Migration and Proliferation
Pulmonary fibrosis is a disease that results in loss of normal lung architecture, but the signaling events that drive tissue destruction are incompletely understood. Wnt/β-catenin signaling is important in normal lung development, but whether abnormal signaling occurs in lung fibrosis due to systemi...
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Hlavní autoři: | Lam, Anna P., Flozak, Annette S., Russell, Susan, Wei, Jun, Jain, Manu, Mutlu, Gökhan M., Budinger, G. R.Scott, Feghali-Bostwick, Carol A., Varga, John, Gottardi, Cara J. |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
American Thoracic Society
2011
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262680/ https://ncbi.nlm.nih.gov/pubmed/21454805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0113OC |
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